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Mechanisms of action of glucagon-like peptide 1 in the pancreas [J]
These can include nausea, vomiting, diarrhea, and constipation
Furthermore, exenatide has been demonstrated to mitigate mitochondrial oxidative stress, reduce Ca 2 overload, inhibit fission, and close the mitochondrial permeability transition pore (mPTP), collectively preventing cardiomyocyte apoptosis by inhibiting the release of proapoptotic proteins such as cytochrome c and caspase-3 [94]
After loading, transition to maintenance dosing of 1000 mcg every 1 to 4 weeks depending on response and follow-up testing
C., & Heymsfield, S
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