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LAMP2A, LAMP2B and LAMP2C: similar structures, divergent roles
Phase II Clinical Data Jastreboff 2023 (NEJM) reported 24.2% bodyweight reduction at 48 weeks - the largest effect size published for any metabolic peptide in clinical trials
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Surgical intervention remains important for complications including strictures, fistulas, abscesses, or medically refractory disease
Avoid eating within three hours of bedtime, as lying down with a full stomach exacerbates delayed gastric emptying
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