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Researchers at the University of Pennsylvania analyzed health records from roughly 12,004 adults with Type 2 diabetes who started taking GLP-1 medications between 2019 and 2024, comparing them with tens of thousands of other patients using two other diabetes drugs, SGLT-2 inhibitors and DPP-4 inhibitors

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Most retatrutide-related diarrhea is mild to moderate, peaks during dose escalation, and resolves within 8 to 12 weeks for the majority of participants

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According to this review, GLP-1 medication seemed most beneficial to the following groups: those higher starting weight and BMI those without diabetes younger females people who used GLP-1s for longer durations A study funded by WW but carried out by independent research teams found that after 3 months, people following a WW program lost an average of 3.8 kg compared to those on a do it yourself weight loss plan, who lost around 1.8 kg