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This made it less practical for research designs that benefited from sustained or once-weekly exposure profiles

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doi:10.1016/j.freeradbiomed.2008.10.040 Tsai CC, Chen HS, Chen SL, Ho YP, Ho KY, Wu YM, Hung CC (2005) Lipid peroxidation: a possible role in the induction and progression of chronic periodontitis

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