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Contact your GP, diabetes specialist nurse, or NHS 111 if: Headaches are persistent, worsening, or significantly impacting daily activities despite simple management measures You experience frequent hypoglycaemic episodes (blood glucose below 4 mmol/L) [31] [32] You have signs of dehydration such as reduced urine output, excessive thirst, or dizziness when standing Side effects are affecting medication adherence or quality of life You develop new or unusual symptoms that concern you Headaches follow a different pattern from any pre-existing headache disorder Healthcare professionals can assess whether headaches are likely related to GLP-1 therapy or require investigation for alternative causes
Thats not the medication failing
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Glucose-dependent insulin secretion & metabolic improvements: GLP-1 improves post-meal insulin secretion and lowers glucagon, which improves glycemia and can reduce metabolic drivers of weight gain
Manufacturers even advise starting at a low dose and titrating slowly (e.g
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