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GLP-1s were developed for blood sugar regulation in diabetes patients and curb appetite by mimicking the natural GLP-1 hormone found in the lower intestine, simulating insulin release from the pancreas in response to eating or drinking

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The drugs also appear to reduce neuroinflammation, scavenge free radicals, and limit damage to neurons

However, as our understanding of cell signaling and regulatory pathways has developed, so has the involvement of GSH homeostasis in many other key processes, including regulation of cell proliferation and apoptosis and post-transcriptional modification of proteins through S-glutathionylation