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Oxidative stress and Mitotracker staining assays were performed by Laboratory 1 only, whereas tissues material exposure for high-throughput transcriptomics analysis was performed by Laboratory 2

Diagnostic criteria used in AD and MCI AD patients were identified primarily using the Diagnostic and Statistical Manual of Mental Disorders (DSM) [63] and/or the National Institute of Neurological and Communicative Diseases and Stroke/Alzheimers Disease and Related Disorders Association [64]

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