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For instance, incorporating N-acetylcysteine (NAC), a precursor to glutathione, into the formulation may help maintain glutathione levels and potentially enhance the overall therapeutic effect
Similarly, Dings research team engineered a system linking two shRNA transcription plasmids targeting MDR-related genes (P-glycoprotein and survivin) to doxorubicin (DOX)-loaded DNA origami via disulfide bonds [57]
These enzymes play a significant role in detoxifying reactive oxygen species (ROS) that can damage sperm DNA, proteins, and lipids
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