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Retatrutide is a triple receptor agonist that activates GLP-1, GIP, and glucagon receptors simultaneously, whereas semaglutide activates only the GLP-1 receptor and tirzepatide activates both GLP-1 and GIP receptors
The closest human data comes from CB4211, a MOTS-c analog tested in a Phase 1a/1b study
If you are working with a 20 mg/mL concentration , a 0.5 mL syringe handles most doses comfortably
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