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Obesity Research & Clinical Practice, 16(3), 275-284

The identification of dysregulated incretin secretion and action in both obesity and diabetes led to the revolutionary discovery of incretin-based drugs, such as glucagon-like peptide 1 (GLP-1) receptor agonists (RAs) and dual glucose-dependent insulinotropic peptide (GIP)/GLP-1 RAs [24,25,26,27,28]

Tirzepatide: A Step Forward in Dual Agonism Tirzepatide is already FDA-approved for both type 2 diabetes ( Mounjaro ) and chronic weight management ( Zepbound )

Several important patterns emerged from these cases

Sudo-Szopiska I, Kwiatkowska B, Prochorec-Sobieszek M, Maliski W