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Exercise-dependent absorption: Physical activity increases blood flow to muscles, which can accelerate absorption unpredictably

34,35 Subsequently, GLP-1 undergoes enzymatic degradation facilitated by dipeptidyl peptidase IV (DPP-4), leading to the loss of its biological efficacy

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Interestingly, treatment withdrawal did not completely restore the mRNA transcripts, and a similar effect was observed for vitamin D metabolism genes and genes associated with NAFLD which was persistently higher, suggesting the epigenetic association between GSH deficiency and vitamin D metabolism genes