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There is then output to the sympathetic nervous system, the thyroid axis, the limbic system, and back to the vagus, which subsequently manages food intake and energy expenditure
The midsection appears flatter, tighter
Low-to-moderate intensity cardio (brisk walking, cycling at conversation pace, light jogging) performed in this window maximizes fat oxidation because the exercise intensity keeps the body in a predominantly fat-burning metabolic state
The protocol is flexible enough to serve both goals
As monotherapy, cagrilintide produced 11.8% weight loss in the Phase 3 REDEFINE 1 trial at 68 weeks with the 2.4 mg dose
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