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She specializes in obesity medicine and sees patients at CU Medicine Weight Management CU Anschutz Health and Wellness Center.

Patients should be counseled to contact their healthcare provider if they experience persistent vomiting, diarrhea, or signs of dehydration that do not improve with increased fluid intake

However, preclinical studies demonstrate therapeutic effects with once-daily or even less frequent administration, suggesting tissue distribution, receptor binding, or cellular signaling effects extend beyond plasma clearance

A significant contributing factor to the prevalence of T2DM is obesity, which is strongly associated with serious consequences such as chronic kidney disease, hypertension, stroke, and liver disease that impair both the quality and quantity of life as life expectancy declines with rising body mass index (BMI) [2]

In severe cases, surgical intervention can also be considered