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The single-serve sachets are convenient for traveling, and the product dissolves well in water, with no taste or gritty texture

Advantages of Metformin Proven Safety and Efficacy: Extensively studied and used for decades, metformins safety and effectiveness are well-established

Acknowledgements We thank Junko Sato and Mayumi Suda and the Biomedical Research Unit of Tohoku University Hospital for technical assistance with the experiments

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GLP-1 receptor agonists slow down gastric emptying early in treatment, but their effectiveness starts to decrease within 1-2 weeks [24]