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Inclusion criteria required participants to be over age 18, read and speak English, have a Hoehn & Yahr score between 2 and 3 (bilateral disease, not severely disabled), and have three or more of the required positive criteria for the diagnosis of definite PD from Step 3 of the UK Brain Bank Diagnostic Criteria for PD

Remove the vent needle first, then the mixing syringe

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Every patient is under the care of a licensed medical provider who conducts a thorough review, orders labs if necessary, and manages the treatment plan