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Among them, SIRT1 is the most studied for its role in fat metabolism, muscle preservation, and mitochondrial health

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Uncommon but notable adverse effects include: Hypokalaemia (low potassium) can occur during initial treatment of severe megaloblastic anaemia, as rapid cell production consumes potassium

Patients should be offered this alternative after an informed discussion on the advantages and disadvantages of both treatment options. oral vitamin B12 is an effective alternative to vitamin B12 IM injections Cochrane Review

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