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Management of hyperglycaemia in type 2 diabetes, 2022
adults have obesity, and 15.8% live with diabetes, including 4.5% who remain undiagnosed
About this article Cite this article Hong, CT., Chen, JH
In osteosarcoma, a distinct subpopulation of CD36+ CAFs has been identified that internalizes oxidized low-density lipoprotein (OxLDL) and activates the PPARG-FABP4 metabolic axis, leading to secretion of ANGPTL4
Non-pharmacological interventions (weight loss 7-10%, Mediterranean diet, and physical activity) are represented as the therapeutic basis, together with pharmacological strategies under investigation or clinical use (THR- agonists, FGF-21 analogs, pan-PPAR modulators, GLP-1 RAs, GLP-1/GIP, SGLT-2 inhibitors, metformin, and statins)
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