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Incretin release from gut is acutely enhanced by sugar but not by sweeteners in vivo

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Study groups We used an active comparator, new-user design to emulate a clinical trial, in which participants are newly initiated on studys medications

What Would Change This View A negative RCT in living skin If a properly powered randomized trial of at-home microinfusion with GHK-Cu versus matched topical control failed to show histologic or photographic differences at 12 weeks, that result would shift the position of this article from "biologically plausible recommendation" to "interesting hypothesis pending data." A safety signal in long-term at-home users If the consumer at-home microinfusion category began producing case reports of infection, scarring, or persistent dermal damage at rates higher than baseline microneedling, the depth recommendation would tighten or the route would be deprecated

Li J, Liu J, Xu Y, Wu R, Chen X, Song X, et al.Tumor heterogeneity in autophagy-dependent ferroptosis