LY3437943, a novel triple glucagon, GIP, and GLP-1 receptor agonist
If you have not tried standard titration with a 2mg starting dose and 4-week escalation intervals, you have not given weekly dosing a fair chance
Methods Animals Male Swiss mice at 12 weeks of age (N = 40) were divided into 5 groups (n = 8 each) (Table 1) and kept in the vivarium of the State University of Montes Claros (UNIMONTES), Minas Gerais (MG), under standard temperature [22 2C], air humidity between 60 5%, 12h light/dark cycle, low sound levels (below 40 dB) with a balanced diet (50.3% carbohydrates, 41.9% protein and 7.8% fat (2.18 kcal/g Purina-Labine ) and filtered tap water ad libitum [38]
the gut and brain adapt to a given exposure over a few weeks, so introducing the drug at a low dose and stepping up gradually lets tolerance develop before the next increment
The oil is also an excellent massage base