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Seek immediate medical attention (attend A&E or call 999) if you experience: Large volumes of blood in the stool or blood clots Melaena black, tarry, foul-smelling stools suggesting upper gastrointestinal bleeding Dizziness, light-headedness, or fainting , which may indicate significant blood loss and haemodynamic compromise Rapid heart rate, pallor, or shortness of breath signs of anaemia or shock Severe, persistent abdominal pain or distension Vomiting blood (haematemesis) or coffee-ground material Arrange an urgent GP appointment if: You notice persistent or recurrent small amounts of bright red blood on toilet paper or mixed with stool You have unexplained weight loss, change in bowel habit, or persistent abdominal discomfort You are aged over 40 years and experiencing new-onset rectal bleeding You have a family history of colorectal cancer or inflammatory bowel disease According to NICE guidance (NG12) , patients should be referred on an urgent suspected cancer pathway (within two weeks) in several scenarios, including: adults aged 50 and over with unexplained rectal bleeding
Linzess is a brand-name medication that contains the active ingredient linaclotide
Converting milligrams to units on a syringe This is where things get tricky with multi-dose vials, and it is the source of dosing confusion that the FDA has specifically warned about
semaglutide (Ozempic) compare directly
Here's what I, as a physician, see in the current scientific landscape
