what's the average weight loss on semaglutide Ozempic Results: What to Expect Tirzepatide causes more weight loss

The schedule above represents the minimum recommended time at each level, not a rigid requirement to increase every four weeks

Dual agonists like tirzepatide may deliver larger average weight changes in some groups, while semaglutide at a weight-management dose carries gold-standard cardiovascular-outcome evidence in a defined population

The DM control group consisted of patients with T2DM who were prescribed insulin or glucose-lowering drugs but not incretin-based drugs (GLP-1 RAs or DPP-4 inhibitors)

doi: 10.1038/s41586-018-0287-8 185 YaoHLanJLiCShiHBrosseauJ-PWangHet al

That aligned with my real-world experience (oysters 1224 hours of flu-like misery), so cutting them has been a win