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Mirabile, theres another significant benefit to this program

10.1016/j.cell.2018.10.025 32 KobilkaB

The one-carbon pool controls mitochondrial energy metabolism via complex I and iron-sulfur clusters

MOTS-c is a 16-amino acid peptide encoded by the 12S rRNA region of mitochondrial DNA, commonly referenced in scientific literature for AMPK signaling, glucose and lipid metabolism, mitochondrial-to-nuclear communication, and age-related metabolic research in laboratory and preclinical models

The right dose is the dose that leads to the biggest improvement in your symptoms without adverse effects outweighing the benefits