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20 th CUEC Chulalongkorn Endocrine Conference 18 20 2567 (macrovascular complications) (microvascular complications) (treatment inertia) (hyperglycemia) (1) (cardiovascular events) (2) (diabetes remission) American Diabetes Association 2025 1 Glucagon-like peptide-1 receptor agonist (GLP-1 RA) (major adverse cardiac event, MACE) (cardio-vascular death, CV death) (nonfatal myocardial infarction) (nonfatal stroke) 1 2 GLP-1 RA Glucagon-like peptide-1 (peptide hormone) GLP-1 (glucose-dependent insulin secretion) (glucagon) GLP-1 pancreatic -cell apoptosis GLP-1 GLP-1 dipeptidyl peptidase-4 (DPP-4) GLP-1 RA DPP-4 GLP-1 RA salcaprozate sodium sodium N-[8-(2-hydroxybenzoyl)amino] caprylate (SNAC) (lipophilicity) (3) oral semaglutide GLP-1 RA oral semaglutide SNAC semaglutide 4 3 1 7 14 Watson L, Das R, Farquhar R, Langerman H, Barnett AH
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