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Su mecanismo de accin y efectos se derivan de la potenciacin del efecto anorexiante de sus tres componentes, manteniendo el retraso en el vaciamiento gstrico, a lo que aade el efecto incretnico, insulinosensibilizador, de acumulacin en tejido adiposo subcutneo de GIP y la capacidad termognica y lipoltica de GCG (tabla 2)54
Figure 2 5 Clinical research progress and safety evaluation 5.1 Clinical efficacy studies Tirzepatide, a novel dual GLP-1 and GIP receptor agonist, has demonstrated remarkable efficacy in the management of type 2 diabetes and obesity, as evidenced by multiple high-quality clinical trials (43, 44)
From increasing metabolism or muscle growth to strengthening the immune system
All three elephants had a history of EEHV detection and pre-existing humoral immunity, consistent with latent infection in adult animals prior to the study 42
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