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They were developed on the basis of either human GLP-1 or exendin-4, a 39-amino acid peptide isolated from the Gila monster ( Heloderma suspectum ) venom, which shares 53% homology with GLP-1 [38]
Hwang E, Portillo B, Williams KW.New 11.Direct and Indirect Effects of Liraglutide on Hypothalamic POMC and NPY/AgRP Neurons - Implications for Energy Balance and Glucose Control.Molecular Metabolism
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Limit the number of punctures through the rubber stopper, as repeated puncturing can introduce contaminants and causes rubber coring (small rubber particles breaking off into the solution)
