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Abstract Colistin is a polymyxin antibiotic currently experiencing renewed clinical interest due to its efficacy in the treatment of multidrug resistant (MDR) bacterial infections
Mu receptor occupancy results in K+ channel opening (hyperpolarization), Ca2+ channel closure ( glutamate, Sub P, CGRP), Na+ channel inhibition (hyperpolarization)
2021 PMID: 33683075 Wu R, Cotliar J
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doi:10.1021/jm00132a010
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