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What to Expect During and After Your B12 Injection During the injection: Vitamin B12 injections are typically administered by a practice nurse at your GP surgery

Current evidence suggests that B12 can potentially trigger acne in susceptible individuals, though this does not affect everyone

Another study published in the Journal of Psychopharmacology found that B12 supplements improved mood and reduced symptoms of depression in individuals with depression

Some might benefit from weekly injections, while others might need them less often for best results

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