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Third, while changes in copper transporters, DLAT, and GSH levels were interpreted in the context of cuproptosis based on prior literature, these associations remain indirect

According to the included studies, lycopene may show high promise in the management of digestive precancerous lesions, such as relieving mouth opening and burning sensation of oral submucous fibrosis (OSF), presenting potentially equivalent efficacy on managing oral lichen planus (OLP) as steroids and alleviating gastrointestinal precancers symptoms, meanwhile lowering colon cancer risk

Natural Medicines Comprehensive Database rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, and Insufficient Evidence to Rate (detailed description of each of the ratings)

Available from: Binder, A., Ali, A., Chawla, R., Aziz, H