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Literatures indicated that the potential factors of IS consist of an overabundance of reactive oxygen species (ROS) (2), DNA damage, neuroinflammation (3), cell death, and bloodbrain barrier (BBB) damage (3)
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Th ose animals in the fourth group were treated with 0.1% phenobarbitone in drinking water for 5 days and were sacrificed 24 hours after the last treatment
LYCOPENE : Acts as a powerful antioxidant