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The benefit comes from replacing whats missing, not from extra B12 on top of normal levels

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The more underlying issues you have, your body will likely protest and need extended adjustment time when flooded with B12 Are Certain Types of B12 Injections More Likely To Cause Symptoms

Because nutrients bypass the digestive process, vitamin injections may provide more direct absorption for individuals who have difficulty maintaining optimal nutrient levels through diet or supplements alone

for some of the changes, it has been demonstrated that they increase the concentration of the so-called inactive B12, but not the active B12