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Glutathione deficiency and oxidative stress have been implicated in the pathogenesis of neurological diseases such as Parkinson's disease, Alzheimer's disease, and multiple sclerosis
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Suppose a reactive Cys is important to protein function
Triterpenoids CDDO and CDDO-Me down-regulate FLIP expression and sensitize AML cells to TRAIL-induced apoptosis
doi:10.1097/MOG.0b013e3283505a3b
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