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For the treatment of adults with insufficiently controlled type 2 diabetes mellitus as an adjunct to diet and exercise: as monotherapy when metformin is considered inappropriate due to intolerance or contraindications in addition to other medicinal products for the treatment of diabetes
a more favorable option for some patients Side Effects: Black Box Warning: RISK OF THYROID C-CELL TUMORS Reference: rxlist.com (Tanzeum) Dulaglutide Drug Name: Trulicity (FDA Approved 9/18/14) GLP-1 receptor agonist, hypoglycemic Pharmacokinetics: Long acting (half life: 5 days) subcutaneous pen injections weekly dosing (vs daily dosing for some other GLP-1 agonists such as exenatide, liraglutide & lixisenatide) a more favorable dosing option for some patients Side Effects: Black Box Warning: RISK OF THYROID C-CELL TUMORS References: Masharani U, Kroon L (2024): Pancreatic Hormones & Antidiabetic Drugs (Chapter 41)
Due to hormonal changes, she can no longer become pregnant or bear children
Patient Implications The STEP UP trial showed that semaglutide 7.2 mg offers a powerful new weight loss option for people who didnt saw weight loss with current treatments
By the end of the trial, 8 percent of the people in the placebo group had had a nonfatal stroke or heart attack or died due to cardiovascular causes
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