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As the dose increases to the maintenance level (4.5 mg), the volume (1.35 mL) exceeds the capacity of a standard insulin syringe, requiring a larger 3 mL syringe for accurate administration
CPS 2008: Compendium of Pharmaceuticals and Specialties: The Canadian Drug Reference for Health Professionals
Higher water volumes reduce concentration but require a larger draw
Besides, many LAB are also used for the industrial or food grade production of biomolecules like vitamins, exopolysaccharides, polyols etc
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