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Domain 9: Outcome assessor details
GLP-1 impact on psychostimulant and nicotine reward Considering that the mesolimbic reward system is a key target not only for food and alcohol, but also for psychostimulants and nicotine (Koob, 2012)
These may indicate serious complications requiring prompt evaluation
Maximum results achieved after 12 weeks
Our review was based on a systematic PubMed search of randomized controlled trials (RCTs), observational studies, systematic reviews/meta-analyses, literature reviews, and case reports, published up to 2022, evaluating the combined treatment with a GLP-1RA and a SGLT2i in T2DM or prediabetes
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