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1,2 Allergic reactions, including anaphylactic shock, are rare and happen more often with injectable forms

(2009) Glutathione dysregulation and the etiology and progression of human diseases

Clinical trials reveal that DSIP injections significantly reduce ACTH levels in plasma for several hours with minimal impact on cortisol (3)

For TB-500, the agency has said it has identified no human exposure data for drug products containing the peptide and also highlighted potential risks associated with aggregation and impurities