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Patients with obesity are more likely to discontinue GLP-1 therapy than those with diabetes, citing lower perceived necessity, stigma, and limited coverage as key drivers 7
A systematic search of PubMed, EMBASE, Cochrane Library, Web of Science and Google Scholar was conducted up to October 2024 for randomized controlled trials involving adult women with PCOS treated with GLP-1RAs compared to metformin or placebo
According to an IQVIA article, by mid-2025, GLP-1s made up more than half of all diabetes prescriptions and 23% of all first-line starts (up from 3% in 2021), displacing metformin and other cheaper generics that historically start the diabetes treatment journey
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