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Discussion In this cohort study, most patients with overweight or obesity discontinued GLP-1 RA therapy within 1 year, but those without type 2 diabetes had higher discontinuation rates and lower reinitiation rates

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These foods are nutrient-dense, so portion control is essentialpre-portioning into small containers or bags can prevent overconsumption

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Severe obesity, uncontrolled diabetes, or subclinical hypothyroidism with minimal symptoms may justify early use of GLP-1s