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Update: This kept getting worse and using a smaller needle didn't help, so I'm going to switch to once-weekly injections and also dilute the drug with significantly less reconstitution solution (20 mg / mL)
It is a GLP-1 receptor agonist
Animal studies have shown a potential risk of thyroid C-cell tumours, though the relevance to humans is unknown
True pharmacological tolerance, where the same dose produces progressively less receptor activation, has not been demonstrated with tirzepatide in clinical trials
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