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The effect of acylcarnitine on insulin sensitivity is also related to the saturation of acylcarnitine, with myotubes incubated with C16-carnitine exhibiting reduced insulin sensitization, whereas the accumulation of oleoylcarnitine (C18:1-carnitine) and linoleoylcarnitine (C18:2-carnitine) increases insulin sensitization [77]
Another review showed that while some people experienced elevated pancreatic enzyme levels, this did not translate into more cases of pancreatitis , and again, the data were inconclusive
Reed, Daniel
Possible explanations are cortisols stimulation of lipolysis and increase in free fatty acids, suppression of insulin secretion and ketogenesis in the liver
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