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Ozempic is also a GLP-1 receptor agonist, which is FDA-approved for managing type 2 diabetes, reducing the risk of cardiovascular diseases, and preventing kidney failure in patients with chronic kidney disease and type 2 diabetes
However, the mechanism beneath the effect of GSH depletion-induced oxidative stress in RPE cells and the subsequent RPE damage is not well established
The dose-response effect we observed where longer GLP-1 receptor agonist exposure was associated with higher risk strengthens the argument that this association may reflect a true biological effect rather than being due to confounding factors, said study co-author Andrew Mihalache, MD(C), of the Temerty Faculty of Medicine at the University of Toronto, Canada
Why do some women experience stronger side effects from GLP-1 medications in midlife
Contact your healthcare provider if fatigue is severe or persistent, interferes with daily activities, or is accompanied by signs of hypoglycemia, dehydration, severe abdominal pain, persistent vomiting, or other concerning symptoms that may indicate serious adverse effects requiring medical evaluation
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