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16 The tentative conclusion that alterations in postprandial GLP-1 dynamics might contribute to such effects of sleep loss is supported by findings in rats that the GLP-1 analog exendin-4 decreases the rewarding value of food

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Berberine extended-release formulations, when available, spread absorption over a longer period and tend to produce fewer acute GI symptoms than standard-release capsules

Severe or persistent vomiting requires immediate attention due to the risk of dehydration , potential medication malabsorption , and the threat of acute kidney injury

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