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doi: 10.1089/jir.2014.0210 20 NorthR

It is clear that the CNS is necessary for GLP-1R mediated induction of visceral illness as mice with a CNS deletion of the GLP-1R develop conditioned taste aversion (CTA) to lithium chloride but not to liraglutide (Sisley et al., 2014)

In addition to increased uptake of adipose-derived FFA, several factors contribute to hepatic fat deposition: I) Increased fatty acid synthesis from ethanol-induced metabolism (increased NADH from ethanol metabolism induces fatty acid synthesis)