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Moderate Coffee Consumption Increases Plasma Glutathione but Not Homocysteine in Healthy Subjects. Alimentary Pharmacology & Therapeutics , vol

Glutamate is an excitatory neurotransmitter, impairment of glutamate homeostasis has important neuropathological consequences and is associated with a variety of neurological or neurodegenerative diseases [46]

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The appropriate response is clinical assessment, not automatically assuming every symptom is harmless