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Endogenously, GLP-1 is secreted by intestinal L cells in response to food, and has multiple roles: enhancing insulin secretion (in a glucose-dependent way), reducing glucagon secretion, slowing gastric emptying, increasing feelings of fullness/satiety, and improving glucose disposal in peripheral tissues
Phlorizin ameliorates obesity-associated endotoxemia and insulin resistance in high-fat diet-fed mice by targeting the gut microbiota and intestinal barrier integrity
The Alpha-Glucosidase Inhibitors also help with reducing postprandial hyperglycemia (1)
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