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Abbreviations AKI: Acute kidney injury AngII: Angiotensin II Bid: BH3-interacting domain death agonist CCL7: Chemokines C-C motif-ligand 7 CI-AKI: Mitigate contrast-induced AKI CKD: Chronic kidney disease C3a: Complement Components 3a C5a: Complement Components 5a DAMPs: Damage-associated molecular patterns ECM: Extracellular matrix ER: Endoplasmic reticulum FGF10: Fibroblast growth factor 10 GFR: Decreased glomerular filtration rate IL: Interleukin IRI: Ischemia-reperfusion injury MAC: Membrane attack complex MAPKs: Mitogen-activated protein kinases NAC: N-acetylcysteine NF-B: Transcription factor-kappa B NLRP3: NOD-like receptor family, pyrin domain containing 3 RAAS: Renin-angiotensin-aldosterone system ROS: Reactive oxygen species TGF-: Transforming growth factor- TLR4: Toll-like receptor 4 TNF: Tumor necrosis factor References Sluman C, Gudka PM, McCormick K