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PubMed lists well over 100 studies, and the number of annual publications has grown quickly from about 45 results in 2020 to more than 180 in 2025 yet there are still no completed Phase III human trials

Molecular biophysics helps interpret how these markers reflect cellular and molecular changes during rehabilitation, guiding adjustments to treatment strategies

Conclusion: The narrative evidence supports positioning GLP-1RAs as time-limited, preconception metabolic-optimization tools, not as confirmed fertility-enhancing therapies per se

However, studies have shown that it acts directly on the pituitary gland and the hypothalamus, as well as GHRH and somatostatin

Thomas, P