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[13] [14] It remains under clinical investigation, and any reported skin-related symptoms should be interpreted within the context of emerging, rather than fully established, evidence

Doherty et al

One possible explanation is that medications reduce appetite and calorie intake without requiring people to practice the day-to-day behaviors that support long-term maintenance

Nonetheless, any new, severe, or unusual headache pattern warrants clinical evaluation to exclude other causes, particularly if accompanied by neurological symptoms, visual disturbances, or signs of raised intracranial pressure

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