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Glutathione S-conjugates are usually sequestered by distinct ABC transporters from the cytosol into the vacuole for degradation, although breakdown of glutathione, oxidized glutathione and glutathione S-conjugates also happens outside the vacuole 56

The toxicity of LRRK2 mutants is dependent on the increased kinase activity as shown in in vitro and in vivo studies [19]

Anemia and chronic renal failure: a therapeutical approach by reduced glutathione parenteral administration

An alternate pathway for androgen regulation of brain function: activation of estrogen receptor beta by the metabolite of dihydrotestosterone, 5alpha-androstane-3beta,17beta-diol

suggest that the peptides upregulation of cellular movement may mirror the early steps in angiogenesis, where living cells extend and organize into primitive vessel structures to facilitate tissue repair