retatrutide phase 3 trial First data, a Triumph of Science! Michael Weintraub, MD on X:

Reducing caloric intake involves setting calorie limits, cutting calories, or restricting certain food types such as dietary fat

While the nephroprotective effects of SGLT2i were initially derived from secondary endpoints of CV outcome trials (CVOTs), direct confirmation came from dedicated kidney focused trials: CREDENCE (Perkovic et al NEJM 2019| NephJC Summary), DAPA-CKD (Heerspink et al NEJM 2020| NephJC Summary) and finally EMPAKIDNEY (Herrington et al NEJM 2023| NephJC Summary)

Boca Raton, FL: CRC Press (2021)

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Making the Right Choice for Your Health Choosing between oral and injectable GLP-1 medications depends on your personal preferences, lifestyle, and medical needs