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Triple agonist: A single molecule that activates three different receptors at once

10.1038/npp.2014.153 4 BajajJ

These medications work by mimicking glucagon-like peptide-1 (GLP-1), a naturally occurring hormone released in the gastrointestinal tract after eating

Common side effects include: Swelling at the injection site Headaches Flushing or warmth Dizziness If you notice any severe side effects, contact your healthcare provider right away

Under certain conditions, such as sustained membrane depolarization and a reduction in GLP-1 concentration to picomolar levels, there can be a switch between Gs and Gq pathways [14]